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Raghu Machiraju

  • Professor, SBS-Biomedical Informatics
  • Professor, Computer Science & Engineering
  • Professor, Pathology
  • IntDir of Data Analyt Collabor, Translational Data Analytics
  • 779 Dreese Laboratories
    2015 Neil Ave
    Columbus, OH 43210
  • 614-292-6730

Journal Articles


  • Myers,Emma,M; Bartlett,Christopher,W; Machiraju,Raghu; Bohland,Jason,W, 2015, "An integrative analysis of regional gene expression profiles in the human brain." METHODS 73, 54-70 - 54-70.
  • Ding H, Wang C, Huang K, Machiraju R., 2015, "GRAPHIE: graph based histology image explorer." . BMC Bioinformatics. 2015 Suppl 11, no. S10, 1186 - 1186.


  • Li Q, Zachmann G, David F, Huang K, Machiraju R, 2014, "Observing Genomics and Phenotypical Patterns in the Developing Mouse Brain." IEEE Computer Graphics and Applications 4, 88-97 - 88-97.
  • Yates,A; Webb,A; Sharpnack,M; Chamberlin,H; Huang,K; Machiraju,R, 2014, "Visualizing Multidimensional Data with Glyph SPLOMs." COMPUTER GRAPHICS FORUM 33, no. 3, 301-310 - 301-310.
  • Wang,Chao; Machiraju,Raghu; Huang,Kun, 2014, "Breast cancer patient stratification using a molecular regularized consensus clustering method." METHODS 67, no. 3, 304-312 - 304-312.


  • Kalluru V, Machiraju R, Huang K., 2013, "Identify condition-specific gene co-expression networks.." Int J Comput Biol Drug Design 6, no. 1-2, 50-59 - 50-59.
  • Wolock,Samuel,L; Yates,Andrew; Petrill,Stephen,A; Bohland,Jason,W; Blair,Clancy; Li,Ning; Machiraju,Raghu; Huang,Kun; Bartlett,Christopher,W, 2013, "Gene X smoking interactions on human brain gene expression: finding common mechanisms in adolescents and adults." JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY 54, no. 10, 1109-1119 - 1109-1119.
  • Wang C, Pecot T, Zynger D, Shapiro C, Machiraju R, Huang K, 2013, Identifying Survival Associated Morphological Features of Triple Negative Breast Cancer using Multiple Datasets. Journal of the American Medical Informatics Association : JAMIA. Epub:, no. NA, NA - NA.


  • Rink,Cameron; Christoforidis,Greg; Khanna,Savita; Peterson,Laura; Patel,Yojan; Khanna,Suchin; Abduljalil,Amir; Irfanoglu,Okan; Machiraju,Raghu; Bergdall,Valerie,K; Sen,Chandan,K, 2011, "Tocotrienol vitamin E protects against preclinical canine ischemic stroke by inducing arteriogenesis." JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 31, no. 11, 2218-2230 - 2218-2230.
  • Sammet,Steffen; Evans,Kevin,D; Irfanoglu,M,Okan; Strapp,Ashley; Machiraju,Raghu, 2011, "THE FEASIBILITY OF HYBRID AUTOMATIC SEGMENTATION OF AXILLARY LYMPH NODES FROM A 3-D SONOGRAM." ULTRASOUND IN MEDICINE AND BIOLOGY 37, no. 12, 2075-2085 - 2075-2085.
  • Singh, S.; Janoos, F.; Pécot, T.; Caserta, E. et al., 2011, "Identifying nuclear phenotypes using semi-supervised metric learning.." Information processing in medical imaging : proceedings of the ... conference 22, 398-410 - 398-410.
  • Janoos, F.; Singh, S.; Machiraju, R.; Wells, W.M. et al., 2011, "State-space models of mental processes from fMRI.." Information processing in medical imaging : proceedings of the ... conference 22, 588-599 - 588-599.


  • Mosaliganti,Kishore; Pan,Tony; Ridgway,Randall; Sharp,Richard; Cooper,Lee; Gulacy,Alex; Sharma,Ashish; Irfanoglu,Okan; Machiraju,Raghu; Kurc,Tahsin; de Bruin,Alain; Wenzel,Pamela; Leone,Gustavo; Saltz,Joel; Huang,Kun, 2008, "An imaging workflow for characterizing phenotypical change in large histological mouse model datasets." JOURNAL OF BIOMEDICAL INFORMATICS 41, no. 6, 863-873 - 863-873.


  • Mosaliganti,Kishore; Janoos,Firdaus; Sharp,Richard; Ridgway,Randall; Machiraju,Raghu; Huang,Kun; Wenzel,Pamela; deBruin,Alain; Leone,Gustavo; Saltz,Joel, 2007, "Detection and visualization of surface-pockets to enable phenotyping studies." IEEE TRANSACTIONS ON MEDICAL IMAGING 26, no. 9, 1283-1290 - 1283-1290.
  • Sharp,Richard,P; Ridgway,Randall; Mosaliganti,Kishore; Wenzel,Pamela; Pan,Tony; de Bruin,Alain; Machiraju,Raghu; Huang,Kun; Leone,Gustavo; Saltz,Joel,H, 2007, "Volume rendering phenotype differences in mouse placenta microscopy data." COMPUTING IN SCIENCE & ENGINEERING 9, no. 1, 38-47 - 38-47.
  • Wenzel,Pamela,L; Wu,Lizhao; de Bruin,Alain; Chong,Jean-Leon; Chen,Wen-Yi; Dureska,Geoffrey; Sites,Emily; Pan,Tony; Sharma,Ashish; Huang,Kun; Ridgway,Randall; Mosaliganti,Kishore; Sharp,Richard; Machiraju,Raghu; Saltz,Joel; Yamamoto,Hideyuki; Cross,James,C; Robinson,Michael,L; Leone,Gustavo, 2007, "Rb is critical in a mammalian tissue stem cell population." GENES & DEVELOPMENT 21, no. 1, 85-97 - 85-97.
  • Kaur, R.; Machiraju, R.; Nigam, K.D.P., 2007, "Agitation effects in a gas-liquid-liquid reactor system: Methyl ethyl ketazine production." International Journal of Chemical Reactor Engineering 5,


  • Kurc, T.; Hastings, S.; Catalyurek, U.V.; Saltz, J. et al., 2003, "A distributed execution environment for analysis of DCE-MR image datasets." Journal of Digital Imaging 16, no. SUPPL., 4-8 - 4-8.

Papers in Proceedings


  • Wang C, Machiraju R, Huang K "Cancer Patient Integrative Stratification via a Two-step Consensus Clustering of Molecular Expression and Clinical Attributes.." in 2014 AMIA (American Medical Informatics Association) Summit on Translational Bioinformatics,. (4 2014).
  • Zhang, L.; Machiraju, R.; Thompson, D.; Rangarajan, A. et al. "Adaptive boosting for enhanced vortex visualization." (1 2014).


  • Park D-Y, Jones D, Moldovan N, Machiraju R, Pécot T "Robust Detection and Visualization of 
Cytoskeletal Structures in Fibrillar Scaffolds from 3-Dimensional Confocal Images." in IEEE Symposium 
on Biological Data Visualization (BioVis) 2013,. (10 2013).
  • Park, D.Y.; Jones, D.; Moldovan, N.I.; Machiraju, R. et al. "Robust detection and visualization of cytoskeletal structures in fibrillar scaffolds from 3-dimensional confocal image." (1 2013).


  • Zhang, L.; Meng, X.; Machiraju, R.; Thompson, D. "Distance measure in vortex visualization." (10 2012).
  • Pecot,Thierry; Singh,Shantanu; Caserta,Enrico; Huang,Kun; Machiraju,Raghu; Leone,Gustavo "NON PARAMETRIC CELL NUCLEI SEGMENTATION BASED ON A TRACKING OVER DEPTH FROM 3D FLUORESCENCE CONFOCAL IMAGES." in 9th IEEE International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro. (1 2012).


  • Irfanoglu,M,O; Walker,L; Sammet,S; Pierpaoli,C; Machiraju,R "Susceptibility Distortion Correction for Echo Planar Images with Non-uniform B-Spline Grid Sampling: A Diffusion Tensor Image Study." in 14th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI 2011). (9 2011).
  • Singh,Shantanu; Janoos,Firdaus; Pecot,Thierry; Caserta,Enrico; Leone,Gustavo; Rittscher,Jens; Machiraju,Raghu "Identifying Nuclear Phenotypes Using Semi-supervised Metric Learning." in 22nd International Conference on Information Processing in Medical Imaging (IPMI). (1 2011).
  • Janoos,Firdaus; Singh,Shantanu; Machiraju,Raghu; Wells,William,M; Morocz,Istvan,A "State-Space Models of Mental Processes from fMRI." in 22nd International Conference on Information Processing in Medical Imaging (IPMI). (7 2011).
  • Irfanoglu, M.O.; Walker, L.; Sammet, S.; Pierpaoli, C. et al. "Susceptibility distortion correction for echo planar images with non-uniform B-spline grid sampling: A diffusion tensor image study." (10 2011).


  • Janoos F, Irfanoglu O, Afacan O, Machiraju R, Warfield S, Wald L, Morocz I "Brain State Identification from fMRI Using Unsupervised Learning." in Proceedings of Human Brain Mapping. (1 2010).
  • Sammet,S; Irfanoglu,O; Koch,R; Schmalbrock,P; Choi,S; Machiraju,R; Yuh,W; Knopp,M "Diffusion Tensor Imaging and Fibertracking at 7T." in 110th Annual Meeting of the American-Roentgen-Ray-Society. (5 2010).
  • Janoos,Firdaus; Machiraju,Raghu; Sammet,Steffen; Knopp,Michael,V; Warfield,Simon,K; Morocz,Istvan,Akos "Measuring Effects of Latency in Brain Activity with FMRI." in 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro. (1 2010).
  • Singh,S; Raman,S; Caserta,E; Leone,G; Ostrowski,M; Rittscher,J; Machiraju,R "ANALYSIS OF SPATIAL VARIATION OF NUCLEAR MORPHOLOGY IN TISSUE MICROENVIRONMENTS." in 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro. (1 2010).
  • F.Janoos, R. Machiraju, S. Sammet, M.V. Knopp and I.A. Morocz "Unsupervised Learning of Brain States from fMRI Data." in 3th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI) Conference, 2010. (1 2010).


  • Janoos,Firdaus; Nouanesengsy,Boonthanome; Machiraju,Raghu; Shen,Han,Wei; Sammet,Steffen; Knopp,Michael; Morocz,Istvan,A "Visual Analysis of Brain Activity from fMRI Data." in 11th Eurographics/IEEE VGTC Symposium on Visualization (EuroVis 09). (6 2009).


  • Jankun-Kelly, M.; Thompson, D.; Jiang, M.; Shannahan, B. et al. "Vortex characterization for engineering applications." (12 2008).


  • Jankun-Kelly, M.; Thompson, D.S.; Brewer, W.; Jiang, M. et al. "A multistage vortex visualization method." (12 2006).
  • Sharp, R.; Adams, J.; Machiraju, R.; Lee, R. et al. "Simulating transillumination in organic material with near infrared light." (12 2006).
  • Kim, Y.; MacHiraju, R.; Thompson, D. "Path-based control of smoke simulations." (9 2006).


  • Glimcher, L.; Agrawal, G.; Mehta, S.; Jin, R. et al. "Parallelizing a defect detection and categorization application." (12 2005).


  • Lee,J,H; Moghaddam,B; Pfister,H; Machiraju,R "Finding optimal views for 3D face shape modeling." in 6th IEEE International Conference on Automatic Face and Gesture Recognition. (1 2004).


  • Moghaddam,B; Lee,J; Pfister,H; Machiraju,R "Model-based 3D face capture with shape-from-silhouettes." in IEEE International Workshop on Analysis and Modeling of Faces and Gestures (AMFG 2003). (1 2003).


  • Polapally,N,K; Machiraju,R; Panda,D "Feature estimation for efficient streaming." in 7th Symposium on Volume Visualization and Graphics. (1 2002).
  • Jiang,M; Machiraju,R; Thompson,D "Geometric verification of swirling features in flow fields." in IEEE Visualization 2002 Eurovis Conference. (1 2002).


  • Machiraju,R; Fowler,J,E; Thompson,D; Soni,B; Schroeder,W "EVITA - Efficient visualization and interrogation of tera-scale data." in Workshop on Mining Scientific Datasets. (1 2001).
  • Tenginakai,S; Lee,J; Machiraju,R "Salient iso-surface detection with model-independent statistical signatures." in IEEE Visualization Conference. (1 2001).
  • Scoggins,R; Machiraju,R; Moorhead,R,J "Approximate shading for the re-illumination of synthetic images." in IEEE Visualization Conference. (1 2001).


  • Burton, L.C.; Machiraju, R.; Reese, D.S. "Dynamic view-dependent partitioning of structured grids with complex boundaries for object-order rendering techniques." (10 1999).


  • Möller, T.; Mueller, K.; Kurzion, Y.; Machiraju, R. et al. "Design of accurate and smooth filters for function and derivative reconstruction." (10 1998).
  • Machiraju,R; Zhu,Z,F; Fry,B; Moorhead,R "Structure-significant representation of structured datasets." in 8th Annual IEEE Conference on Visualization. (4 1998).